Welcome to the Xu Research Group at Virginia Commonwealth University



Our research focuses on the health issues of blindness, cancer and drug abuse, which have huge socioeconomic implications. Our lab applies engineering principles to advance our understanding of the interactions of therapeutic nanoparticle platforms with biological barriers and disease pathophysiology. This knowledge guides us to better design new biomaterials and nanotherapeutic-based treatments for eye disorders, cancer and other diseases. Our research program operates at the interface of nanoengineering, materials science, and translational medicine. We aim to translate technologies to have a meaningful impact on human health.

Current News



Congratulations to Emma on her bioanalytical research paper (LC-MS/MS method for simultaneous quantification of dexamethasone and tobramycin in rabbit ocular biofluids) being published on Journal of Chromatography B.


Dr. Xu and Dr. Youngman Oh were awarded an collaborative VCU VETAR grant studying a novel targeted therapy for AMD.


Congratulations to Dr. Guihong Chai for being promoted to Research Assistant Professor.

2020 News



Congratulations to Dr. Chai on his recent two pulmonary drug delivery research papers on Am J Resp Cell Mol Bio; and Nanomedicine: NBM. 


Congratulations to Dr. Xuan on her review paper on Drug Discovery Today.


Dr. Qingguo Xu was selected to receive the 2020 VCU School of Pharmacy Emerging Faculty Scholar Award. 


We welcome Arya Bazargani joining our lab as a Ph.D. student in Pharmaceutical Engineering.


Congratulations to Dr. Jin Yang on her paper (sunitinib-malate microparticle inhibiting corneal neovascularization) published in Journal of Controlled Release. 


Congratulations to Dr. Guihong Chai on his paper (new liposomal aerosol) published in Nanomedicine: NBM. 


Congratulations to Tuo (Emma) Meng for passing her PhD candidacy oral exam via Zoom. Thanks to the committee.


Congratulations to Tuo Meng, the 2nd year PhD student in the lab, for winning 2020 CRS-Ocular Delivery Focus Group Trainee Award @CRS_FG_Ocular @CRSScience. Sponsored by @Regeneron.


Congratulations to Vineet Kulkarni for his successful M.S. thesis defense via Zoom. He will join the University of Texas at Austin to pursue his Ph.D. All the best and good luck! 


Guihong Chai, Ph.D., received the prestigious Cystic Fibrosis Foundation (CFF) postdoctoral fellowship, which will provide two years of support for his work on a novel antibiotic aerosol formulation to treat cystic fibrosis-associated lung infections. Look for collaborations with Michael Hindle, Ph.D., at VCU School of Pharmacy's Department of Pharmaceutics; Bruce Rubin, M.D., at VCU School of Medicine's Department of Pediatrics; and Tony Zhou, Ph.D., at Purdue. 


We welcome three new postdoc fellows who recently joined our lab: Lihua Lou, Ph.D.; Wenjing Xuan, Ph.D.; and Aji Alex Moothedathu Raynold, Ph.D. We look forward to rewarding collaborations with these rising stars. 


Big congratulations to Tuo (Emma) Meng for winning both Thakker Award and Schwartz Award, and to John Kwon for winning the Best Poster Award (PharmD) at VCU School of Pharmacy Research and Career day. 


The first stage $1.6m for 2 years of our multi-PI NIH/NIDA UG3 grant ( total 5 years) was funded to develop novel treatments for opioid use disorder. Congratulations to all our co-PIs and collaborators (Charles Okeeffe, Gerry Moeller, Matthew Halquist, Xiuling Lu). 


Dr. Xu received the Association of Ocular Pharmacology and Therapeutics (AOPT) Young Investigator Travel Award, and he will give an oral presentation at the 14th Scientific Meeting of AOPT, New Orleans,  March 7-10, 2019.


Dr. Qingguo Xu will serve as the vice chair for the Controlled Release Society (CRS) Ocular Delivery Focus Group. CRS is the home for experts dedicated to delivery science, including delivery scientists, engineers, clinicians, and technical professionals. The next annual meeting is at Las Vegas #seeyouinVegas2020.


We welcome Hadi Sudarjat to join our lab as a PhD student in Pharmaceutical Sciences program, and Hadi was awardee of the prestigious FullBright Scholar funded by the American Indonesian Exchange Foundation. 


It is a big honor for Dr. Qingguo Xu being named as a Blick Scholar. There are 4 Blick Scholars for the term of 2019-2023. It is made possible by the George and Lavinia Blick Research Fund, an endowment designated for supporting medical research conducted on the MCV Campus of Virginia Commonwealth University. We greatly appreciate the support from the committee and the MCV foundation


John Kwon, P2 PharmD student, joined our lab as a VCU SoP Summer Research Fellow. John’s research is to develop new method for treating glaucoma. Congratulations and Welcome! 


Russell Simmers, a rising junior undergraduate in the VCU Honors College and a undergraduate researcher in Xu's Nanotherapeutics Research lab since 2018, was among 6 to 12 students accepted to the VCU guaranteed admissions program for the VCU School of Medicine. Big Congratulations! 


Dr. Xu is selected as the 2019 CRS Ocular Delivery Focus Group Young Investigator at the CRS annual meeting. The 2019 Controlled Release Society Annual Meeting & Exposition will be held from July 21st-24th, in Valencia, Spain. Thanks for the support from the committee. 


Our invited keynote review paper "Therapeutic implications of nanomedicine for ocular drug delivery" to Drug Discovery Today (IF: 6.85) was published. Congratulations to Tuo (Emma), Vineet, Russell and Vikram.